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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERBB2IP All Species: 13.94
Human Site: T541 Identified Species: 30.67
UniProt: Q96RT1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RT1 NP_001006600.1 1412 158298 T541 K T S E S T T T V K S K V D E
Chimpanzee Pan troglodytes XP_001162761 1412 158257 T541 K T S E S T T T V K S K V D E
Rhesus Macaque Macaca mulatta XP_001088781 1458 163156 T541 K T S E S T T T V K S K V D E
Dog Lupus familis XP_535260 1302 145834 D465 A Q V A F D C D E D K D E R E
Cat Felis silvestris
Mouse Mus musculus Q80TH2 1402 157214 S538 K C V K T S E S T T T K S K L
Rat Rattus norvegicus P70587 1495 167465 N609 E N A N P T A N T E Q T V K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520661 1469 160728 P539 V K T S E G I P V K G Q T E D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q4H4B6 1724 189501 S532 Q A S S S T T S A T S H E D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KRY7 1851 200421 R512 A E T P T E T R T I A N N H Q
Honey Bee Apis mellifera XP_393738 980 109823 D142 N P F E R F P D A I T H I V G
Nematode Worm Caenorhab. elegans O61967 699 77331
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.7 85.9 N.A. 88.8 40.6 N.A. 73.7 N.A. N.A. 25.8 N.A. 24.2 29.1 21.2 N.A.
Protein Similarity: 100 99.8 95.7 88.9 N.A. 93.1 57.3 N.A. 81.6 N.A. N.A. 42.7 N.A. 40.9 44.9 34.3 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 13.3 20 N.A. 13.3 N.A. N.A. 40 N.A. 6.6 6.6 0 N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 46.6 40 N.A. 40 N.A. N.A. 60 N.A. 33.3 20 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 10 10 0 0 10 0 19 0 10 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 19 0 10 0 10 0 37 10 % D
% Glu: 10 10 0 37 10 10 10 0 10 10 0 0 19 10 46 % E
% Phe: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 19 0 10 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 19 0 0 10 0 0 % I
% Lys: 37 10 0 10 0 0 0 0 0 37 10 37 0 19 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 10 0 0 0 10 0 0 0 10 10 0 0 % N
% Pro: 0 10 0 10 10 0 10 10 0 0 0 0 0 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 10 10 0 0 10 % Q
% Arg: 0 0 0 0 10 0 0 10 0 0 0 0 0 10 0 % R
% Ser: 0 0 37 19 37 10 0 19 0 0 37 0 10 0 0 % S
% Thr: 0 28 19 0 19 46 46 28 28 19 19 10 10 0 0 % T
% Val: 10 0 19 0 0 0 0 0 37 0 0 0 37 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _